Book review Essay Example | Topics and Well Written Essays - 250 words

Book review - Essay Example he author’s intention is clear from the start that she wants an apology from the Japanese government and a repatriation for the comfort women whom she believed were aggrieved and should be justly paid. Her paper is also a subtle way of pronouncing that she is supporting the advocacies of pro-comfort women rights. It is addressed to an audience that is working for this commitment. Her articulation of events and history of comfort women agrees with other written articles about the matter. She wrote about the number of about 200,000 women in brothels, and the pains and sexual diseases they have contracted, in the same way it is reported in the Encyclopedia article for comfort women. Author is able to uncover events beyond World War II and takes us to the recent scenarios of confessions of comfort women, investigations and hearings in order to convince the Japanese government to apologize. She was able to unearth researches relevant on the matter from archives and incorporated it in her study that could be useful to other interested researchers. Other topics that she wrote about international responses like that of the US, Canada, Dutch Parliament and EU are also found in numerous articles of research, but nevertheless, a confirmation of evidences. This also shows that the argument Choi had written is backed up by evidences from primary sources. The author is a graduate student at the Bologna Center of the Johns Hopkins University Paul H. Nitze School of Advanced International Studies. Her areas of concentration are International Relations and International Law and

Discussion Topic Essay Example | Topics and Well Written Essays - 500 words - 2

Discussion Topic - Essay Example Homobatrachotoxinin is a member of the family of steroidal alkaloids called Batrachotoxinins (Fig 1). These compounds have a molecular formula of C31H42N2O6, with a molar mass of 538.67g/mol and a density of 1.304g/ml. It is highly toxic and the median lethal dose (LD50) is 0.002 to 0.007 mg/kg depending upon species to species (Daly, 1965). The mechanism of its toxicity is related to its action is on the voltage gated sodium channels present in the cell membrane. Since it is a steroidal alkaloid it can easily access the cell membrane of the predators, and binds to the voltage gated sodium channels and keeps them in a state of depolarization. These compounds bind irreversibly to the sodium channels creating a conformational change in them, that keeps the channels always in a open state. Further they also reduces conductance of these channels leading them to be in a state of less excitability. This impacts the nervous system because the membrane cannot become stabilized to its resting level (generation of resting membrane potential is hampered) which leads to impairment of neuromuscular transmission in the predator leading them into a state of paralysis. Apart from neurotoxicity they are also cardiotoxic as these compounds reduces cardiac conduction, cause arrhythmias and ventricular fibrillation. These compounds are tem perature dependant and are effective at an optimum temperature of 37 degree centigrade and also work best in the alkaline pH range to exert its neurotoxic and cardiotoxic effects (Wang, 2007). Conclusion: My hypothesis was supported by the research that Batrachotoxinins are effective avian chemicals tat are potent against predators however when the environmental temperature or core body temperature of predators increases beyond 37 degree centigrade, this molecule might not impact them and may not act as a chemical defense mechanism of the genus